Sunday, October 09, 2011

People’s Pharmacy: Antidepressants carry suicide risk

QUESTION: A family member took his life while on Cymbalta. He never had been depressed, but when he explained to his physician the suicidal thoughts he was having, the physician doubled his dose of Cymbalta, added Abilify and told him to come back in a week. He died by his own hand instead.

ANSWER: The Food and Drug Administration requires a highlighted warning for Cymbalta and similar drugs: "Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder and other psychiatric disorders. … Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior."


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